HHLA2 Antibody / HERV-H LTR-associating protein 2
Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. [UniProt]
Product Specifications
Specifications
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:25-1:50
UniProt
Q9UM44
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 58-87 from the human protein were used as the immunogen for the HHLA2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, FACS
Purity
Antigen affinity purified
Format
Purified
Limitations
This HHLA2 antibody is available for research use only.
Storage Conditions
Aliquot the HHLA2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the HHLA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of human 1) lung, 2) kidney, 3) pancreas, 4) testis and 5) MDA-MB-453 lysate with HHLA2 antibody. Expected molecular weight: 38-60 kDa depending on glycosylation level.
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