Alpha Lactalbumin Antibody / LALBA

This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells.

Product Specifications

Specifications

Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:25-1:50

UniProt

P00709

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 39-68 from the human protein were used as the immunogen for the Alpha Lactalbumin antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Limitations

This Alpha Lactalbumin antibody is available for research use only.

Storage Conditions

Aliquot the Alpha Lactalbumin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Alpha Lactalbumin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IHC testing of FFPE human breast tissue with Alpha Lactalbumin antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.