DRD2 Antibody / Dopamine D2 Receptor

This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

Product Specifications

Specifications

Western blot: 1:1000-1:2000

UniProt

P14416

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 307-336 from the human protein were used as the immunogen for the DRD2 antibody.

Clonality

Polyclonal

Isotype

Applications

Purity

Antigen affinity purified

Format

Purified

Limitations

This DRD2 antibody is available for research use only.

Storage Conditions

Aliquot the DRD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the DRD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.