ATP7B Antibody

ATP7B is a member of the P-type cation transport ATPase family and a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile.

Product Specifications

Specifications

Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:25-1:50, Immunofluorescence: 1:25

UniProt

P35670

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 1361-1391 from the human protein were used as the immunogen for the ATP7B antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P, FACS, IF

Purity

Protein A purified

Format

Purified

Limitations

This ATP7B antibody is available for research use only.

Storage Conditions

Aliquot the ATP7B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the ATP7B antibody may be required due to differences in protocols and secondary/substrate sensitivity.