SCAP Antibody / SREBP cleavage-activating protein
SCAP is a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
Product Specifications
Specifications
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:50-1:100, Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:50-1:100
UniProt
Q12770
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A portion of amino acids 604-632 from the human protein were used as the immunogen for the SCAP antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, FACS, IF
Purity
Antigen affinity purified
Format
Purified
Limitations
This SCAP antibody is available for research use only.
Storage Conditions
Aliquot the SCAP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.nsjbio.com/tds-pdf/scap-antibody-srebp-cleavage-activating-protein-f54258
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic
Image Legend
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