GCLM Antibody / Glutamate-Cysteine Ligase Regulatory Subunit
GCLM known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
Product Specifications
Specifications
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:25-50, Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25
UniProt
P48507
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 246-274 from the human protein were used as the immunogen for the GCLM antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, FACS, IF
Purity
Antigen affinity purified
Format
Purified
Limitations
This GCLM antibody is available for research use only.
Storage Conditions
Aliquot the GCLM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic
Image Legend
Western blot testing of human HeLa cell lysate with GCLM antibody. Predicted molecular weight ~31 kDa.
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