GPX1 Antibody / Glutathione Peroxidase 1

GPX1 encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence.

Product Specifications

Specifications

Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:25, Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25

UniProt

P07203

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A portion of amino acids 164-193 from the human protein were used as the immunogen for the GPX1 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P, FACS, IF

Purity

Antigen affinity purified

Format

Purified

Limitations

This GPX1 antibody is available for research use only.

Storage Conditions

Aliquot the GPX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the GPX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.