HSD17B13 Antibody / DHB13 / 7-beta hydroxysteroid dehydrogenase 13
HSD17B13 protein is an enzyme that plays a key role in the metabolism of steroids and lipids in the body. Specifically, it is involved in the conversion of various hormones and fatty acids, making it a critical player in maintaining metabolic homeostasis. Additionally, studies have shown that mutations or dysregulation of the HSD17B13 gene can lead to impaired lipid metabolism and contribute to the development of liver diseases such as non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease. HSD17B13 protein is a potential therapeutic target for liver diseases.
Product Specifications
Specifications
Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:250-1:500
UniProt
Q7Z5P4
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 81-110 from the human protein was used as the immunogen for this HSD17B13 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Limitations
This HSD17B13 antibody is available for research use only.
Storage Conditions
Aliquot the HSD17B13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the HSD17B13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasm
Image Legend
IHC testing of FFPE human liver tissue with HSD17B13 antibody. HIER: steam section in pH9 EDTA buffer for 20 min and allow to cool prior to staining.
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