MyD88 Antibody
Myeloid differentiation primary response protein MyD88 is an adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.
Product Specifications
Specifications
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:10-1:50, Flow Cytometry: 1:10-1:50 per million cells in 0.1ml
UniProt
Q99836
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 136-164 from the human protein was used as the immunogen for this MyD88 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Limitations
This MyD88 antibody is available for research use only.
Storage Conditions
Aliquot the MyD88 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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