MyD88 Antibody

Myeloid differentiation primary response protein MyD88 is an adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. It acts via IRAK1, IRAK2 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and increases IL-8 transcription. It may be involved in myeloid differentiation.

Product Specifications

Specifications

Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:10-1:50, Flow Cytometry: 1:10-1:50 per million cells in 0.1ml

UniProt

Q99836

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 136-164 from the human protein was used as the immunogen for this MyD88 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P, FACS

Purity

Antigen affinity

Format

Antigen affinity purified

Limitations

This MyD88 antibody is available for research use only.

Storage Conditions

Aliquot the MyD88 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the MyD88 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

MyD88 antibody flow cytometric analysis of fixed and permeabilized human K562 cells (green) compared to aÂ negative control (blue) . FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.