CTLA4 Antibody / Cytotoxic T-lymphocyte protein 4 / CD152
CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer.
Product Specifications
Specifications
Western blot: 1:1000-1:2000, Immunofluorescence: 1:50-1:100
UniProt
P16410
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 182-210 from the human protein was used as the immunogen for this CTLA4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Limitations
This CTLA4 antibody is available for research use only.
Storage Conditions
Aliquot the CTLA4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CTLA4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
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