SFTPC Antibody / Surfactant protein C
Surfactant protein C is a hydrophobic protein that is primarily found in type II alveolar cells in the lungs. Its main function is to stabilize the lipid layer of pulmonary surfactant, preventing alveoli collapse and maintaining proper lung function. Without sufficient levels of SFTPC protein, individuals may experience respiratory distress and lung diseases such as pulmonary fibrosis and acute respiratory distress syndrome. Research has shown that mutations in the SFTPC gene can lead to various lung disorders, highlighting the role of this protein in maintaining respiratory function.
Product Specifications
Specifications
Western blot: 1:1000-1:2000, Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:200, Flow cytometry: 1:25 per million cells in 0.1ml
UniProt
P11686
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A portion of amino acids 1-30 from the human protein was used as the immunogen for the SFTPC antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IF, IHC-P, FACS
Purity
Antigen affinity purified
Format
Purified
Limitations
This SFTPC antibody is available for research use only.
Storage Conditions
Aliquot the SFTPC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SFTPC antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
IHC testing of FFPE human lung tissue with SFTPC antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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