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YTHDF3 Antibody / YTH domain-containing family protein 3

YTHDF3 belongs to a family of proteins with YTH domains, which are specialized RNA-binding domains that help to recognize and regulate RNA molecules. YTHDF3 specifically plays a key role in the regulation of mRNA degradation and translation, ultimately influencing gene expression. By binding to specific RNA molecules, YTHDF3 can either promote the degradation of the RNA or enhance its translation into proteins. Studies have shown that YTHDF3 can modulate the expression of genes involved in immune responses, development, and cancer progression and may play a role in stem cell differentiation and embryonic development.

Product Specifications

Specifications

Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:10-1:50

UniProt

Q7Z739

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 228-257 from the human protein was used as the immunogen for the YTHDF3 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Limitations

This YTHDF3 antibody is available for research use only.

Storage Conditions

Aliquot the YTHDF3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the YTHDF3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasm

Image Legend

Western blot testing of human 1) HeLa and 2) K562 cell lysate with YTHDF3 antibody. Predicted molecular weight ~64 kDa.

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