MARCO Antibody / SCARA2

MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

Product Specifications

Specifications

Western blot: 1:250-1:500, Flow cytometry: 1:10-1:50, Immunohistochemisty (FFPE) : 1:50-1:100

UniProt

Q9UEW3

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 13-40 from the human protein was used as the immunogen for this MARCO antibody.

Clonality

Polyclonal

Isotype

Applications

WB, FACS, IHC-P

Purity

Antigen affinity

Format

Antigen affinity purified

Limitations

This MARCO antibody is available for research use only.

Storage Conditions

Aliquot the MARCO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the MARCO antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Membrane, cytoplasm

Image Legend

IHC staining of FFPE human tonsillitis tissue with MARCO antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.