Cx40 Antibody / Connexin 40 / GJA5
Connexin 40 protein, also known as Cx40, GJA5 and Gap junction alpha-5 protein, plays a role in cell communication and proper function within the body. In the brain, Connexin 40 helps facilitate communication between neurons, allowing for proper cognitive function and coordination. Research suggests that disruptions in Connexin 40 expression may contribute to neurological disorders such as epilepsy and Alzheimer's disease. In the immune system Gap junctions formed by Connexin 40 facilitate the transfer of signaling molecules between immune cells, enabling a coordinated response to pathogens and foreign invaders.
Product Specifications
Specifications
Western blot: 1:2000-1:4000, Immunohistochemistry (FFPE) : 1:100-1:500
UniProt
P36382
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 102-134 from the human protein was used as the immunogen for this Cx40 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P
Format
Purified
Limitations
This Cx40 antibody is available for research use only.
Storage Conditions
Aliquot the Cx40 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Cx40 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of 1) human Jurkat, 2) human HepG2 and 3) mouse brain tissue lysate with Cx40 antibody. Predicted molecular weight ~40 kDa.
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