Ephrin type-A receptor 4 Antibody / EphA4

Ephrin type-A receptor 4, also known as Eph4A, is a member of the Eph receptor family. These receptors are involved in mediating cell-to-cell communication and are critical for various physiological processes such as tissue patterning, neuronal development, and immune response. One of the key functions of Eph4A is its role in axon guidance during neuronal development. Studies have shown that Eph4A is essential for establishing proper neuronal connections in the developing brain. Disruption of Eph4A signaling has been linked to various neurological disorders, highlighting the importance of this receptor in brain development. In addition to its role in neuronal development, Eph4A has also been implicated in cancer progression. Aberrant expression of Eph4A has been observed in various types of cancer, and targeting this receptor has shown promising results in inhibiting tumor growth and metastasis. Furthermore, Eph4A has been shown to play a role in immune response regulation. By modulating the activity of immune cells, Eph4A can influence the inflammatory response and contribute to the maintenance of immune homeostasis.