DEPDC5 Antibody / DEP domain-containing protein 5

The DEPDC5 gene encodes DEP domain-containing protein 5, a protein which contains a DEP (disheveled, EGL-10, pleckstrin) domain. This domain is known for its involvement in signal transduction and cellular communication, highlighting the importance of DEPDC5 in coordinating crucial cellular processes. DEP domain-containing protein 5 has been implicated in the regulation of cellular signaling pathways, including the mechanistic target of rapamycin complex 1 (mTORC1) pathway. By interacting with key proteins in this pathway, DEPDC5 plays a critical role in maintaining cellular homeostasis and growth. Mutations in the DEPDC5 gene have been linked to various neurological disorders, including familial focal epilepsy.