CYP3A4 Antibody / Cytochrome P450 3A4

CYP3A4 is a member of the cytochrome P450 enzyme family, which plays a role in the metabolism of various drugs and xenobiotics in the human body. CYP3A4 is responsible for metabolizing over half of all clinically prescribed drugs, making it one of the most important drug-metabolizing enzymes in the body.

Product Specifications

Specifications

Western blot: 1:500-1:1000, Flow cytometry: 1:10-1:50 per million cells in 0.1ml, Immunohistochemistry (FFPE) : 1:10-1:50

UniProt

P08684

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 228-255 from the human protein was used as the immunogen for the CYP3A4 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, FACS, IHC-P

Purity

Antigen affinity purified

Format

Purified

Limitations

This CYP3A4 antibody is available for research use only.

Storage Conditions

Aliquot the CYP3A4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the CYP3A4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IHC staining of FFPE human liver tissue with CYP3A4 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.