Phorbolin 1 Antibody / APOBEC3A

Phorbolin 1/PHO1/APOBEC3A/Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A is part of a family of enzymes that are involved in the editing of RNA and DNA molecules. Phorbolin 1/APOBEC3A specifically acts as a barrier to prevent the replication of viral DNA within cells, making it a crucial component of the innate immune system. It also plays a pivotal role in preventing the development of certain cancers. Studies have shown that this protein can inhibit the growth of cancer cells by inducing mutations in their genetic material.

Product Specifications

Specifications

Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:50-1:100

UniProt

P31941

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for the Phorbolin 1 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Format

Purified

Limitations

This Phorbolin 1 antibody is available for research use only.

Storage Conditions

Aliquot the Phorbolin 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Phorbolin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Nuclear, cytoplasmic

Image Legend

IHC staining of FFPE human prostate carcinoma tissue with Phorbolin 1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.