NUAK1 Antibody / ARK5

NUAK1, also known as AMPK-related protein kinase 5 (ARK5), is a key player in regulating energy metabolism and cell survival. It has been linked to various cellular processes, including cell proliferation, autophagy, and the response to stress. Studies have shown that NUAK1 may be involved in the development of certain cancers, making it a promising target for anti-cancer therapies. Additionally, NUAK1 has been linked to conditions such as diabetes and neurodegenerative diseases, suggesting that it could have implications for a wide range of health conditions.

Product Specifications

Specifications

Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:50-1:100

UniProt

O60285

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 604-634 from the human protein was used as the immunogen for the NUAK1 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Format

Purified

Limitations

This NUAK1 antibody is available for research use only.

Storage Conditions

Aliquot the NUAK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the NUAK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasm, Nucleus

Image Legend

IHC staining of FFPE human breast cancer tissue with NUAK1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.