SLC11A2 Antibody / Solute carrier family 11 member 2

SLC11A2, also known as Solute carrier family 11 member 2 and Divalent metal ion transporter 1 (DMT1), SLC11A2 is responsible for transporting essential metal ions, such as iron and manganese, across cell membranes. These metal ions are vital for various biological processes, including oxygen transport, energy production, and DNA synthesis. Research has shown that mutations in the SLC11A2 gene can lead to various health conditions, such as iron-deficiency anemia and neurodegenerative disorders.

Product Specifications

Specifications

Western blot: 1:1000-1:2000, Immunofluorescence: 1:10-1:50

UniProt

P49281

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A portion of amino acids 262-291 from the human protein was used as the immunogen for the SLC11A2 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IF

Purity

Antigen affinity purified

Format

Purified

Limitations

This SLC11A2 antibody is available for research use only.

Storage Conditions

Aliquot the SLC11A2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the SLC11A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasm

Image Legend

Western blot testing of 1) human PANC-1, 2) mouse cerebellum and 3) rat cerebellum tissue lysate with SLC11A2 antibody. Predicted molecular weight ~63 kDa.