VGluT2 Antibody / Vesicular glutamate transporter 2 / SLC17A6

VGluT2, short for Vesicular Glutamate Transporter 2, is a protein that is responsible for packaging and transporting glutamate into synaptic vesicles. These vesicles then release glutamate into the synaptic cleft, where it binds to receptors on the postsynaptic neuron, leading to the transmission of signals between neurons. Research has shown that VGluT2 is predominantly expressed in specific brain regions, such as the cerebellum, hippocampus, and cortex, where it plays a crucial role in modulating synaptic transmission and plasticity. Dysfunction of VGluT2 has been linked to various neurological disorders, including epilepsy, schizophrenia, and neurodegenerative diseases.