Myosin-binding protein C Antibody / MYBPC3

Myosin-binding protein C is a thick filament-associated protein that interacts with myosin and actin to regulate muscle contraction. It acts as a molecular ruler, fine-tuning the interactions between myosin and actin to ensure proper muscle function. MYBPC3 mutations can disrupt this delicate balance, leading to impaired muscle contraction and potential cardiac complications. Mutations in the MYBPC3 gene have been associated with hypertrophic cardiomyopathy (HCM), a condition characterized by thickening of the heart muscle. These mutations can disrupt the normal function of Myosin-binding protein C, leading to abnormal muscle contraction and potentially life-threatening complications.