B2AR Antibody / Beta-2-Adrenergic receptor / ADRB2

The Beta-2-Adrenergic receptor is a protein that is found on the surface of cells, particularly in the lungs, heart, and smooth muscle tissue. It is a member of the G-protein coupled receptor family which transmits signals from outside the cell to the inside, triggering a cascade of cellular responses. The Beta-2-Adrenergic receptor plays a critical role in regulating various physiological functions, including bronchodilation, heart rate, and glucose metabolism. Dysregulation of the Beta-2-Adrenergic receptor has been implicated in a variety of diseases, such as asthma, chronic obstructive pulmonary disease, and heart failure.

Product Specifications

Specifications

Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:10-1:50

UniProt

P07550

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 236-264 from the human protein was used as the immunogen for the B2AR antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Purified

Limitations

This B2AR antibody is available for research use only.

Storage Conditions

Aliquot the B2AR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the B2AR antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cell membrane, cytoplasm

Image Legend

IHC staining of FFPE human hepatocarcinoma tissue with B2AR antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.