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FCRL4 Antibody / Fc receptor-like protein 4

Fc receptor-like proteins (FCRLs) are a family of receptors that resemble Fc receptors, which are usually found on immune cells and are involved in recognizing and binding to antibodies. FCRL4, in particular, has been shown to be expressed on B cells and T cells, suggesting its involvement in immune regulation. One of the key functions of FCRL4 is its ability to modulate the activation and signaling pathways of immune cells. Studies have indicated that FCRL4 may play a role in regulating B cell responses, including antibody production and immune cell activation. Additionally, FCRL4 has been linked to autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, highlighting its importance in immune dysregulation.

Product Specifications

Specifications

Western blot: 1:1000-1:2000, Flow cytometry: 1:10-1:50 per million cells in 0.1ml

UniProt

Q96PJ5

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 480-507 from the human protein was used as the immunogen for the FCRL4 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, FACS

Purity

Antigen affinity

Format

Purified

Limitations

This FCRL4 antibody is available for research use only.

Storage Conditions

Aliquot the FCRL4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the FCRL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human 1) Daudi and 2) Raji cell lysate with FCRL4 antibody. Predicted molecular weight ~57 kDa.

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