Fibrinogen alpha Antibody / FGA

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.

Product Specifications

Specifications

Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:10-1:50, Immunofluorescence: 1:10-1:50

UniProt

P02671

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 116-144 from the human protein was used as the immunogen for this Fibrinogen alpha antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P, IF

Format

Purified

Limitations

This Fibrinogen alpha antibody is available for research use only.

Storage Conditions

Store at 4°C for up to one month. For long term, aliquot the Fibrinogen alpha antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the Fibrinogen alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human blood plasma lysate with Fibrinogen alpha antibody. Predicted molecular weight ~70 kDa (alpha isoform), ~95 kDa (alpha-E isoform) .