NRXN1 Antibody / Neurexin 1 beta
Neurexin 1 is primarily known for its role in the formation and maintenance of synapses, the connections between neurons that allow for communication in the brain. It acts as a cell adhesion molecule, helping to guide the development of synapses and ensuring proper signaling between neurons. Studies have shown that mutations in the NRXN1 gene can lead to disruptions in synaptic function, ultimately impacting brain development and function. These mutations have been associated with a variety of neurological disorders, including autism spectrum disorder, schizophrenia, and intellectual disabilities.
Product Specifications
Specifications
Western blot: 1:1000-1:2000
UniProt
P58400
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A portion of amino acids 77-110 from the human protein was used as the immunogen for this NRXN1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Limitations
This NRXN1 antibody is available for research use only.
Storage Conditions
Store at 4°C for up to one month. For long term, aliquot the NRXN1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
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