GSDMA Antibody / Gasdermin-A
Gasdermin-A is a protein that plays a crucial role in programmed cell death, or pyroptosis, a process that is essential for the body to eliminate infected or damaged cells. This protein acts as a pore-forming molecule, causing the cell membrane to rupture and release pro-inflammatory molecules that signal the immune system to clear away the debris. Recent studies have shown that dysregulation of Gasdermin-A can lead to a variety of health issues, including autoimmune diseases, inflammatory disorders, and even cancer.
Product Specifications
Specifications
Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:50-1:100, Flow cytometry: 1:10-1:50 per million cells in 0.1ml
UniProt
Q96QA5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 66-94 from the human protein was used as the immunogen for this GSDMA antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Limitations
This GSDMA antibody is available for research use only.
Storage Conditions
Store at 4°C for up to one month. For long term, aliquot the GSDMA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasm, cell membrane
Image Legend
IHC staining of FFPE human skin tissue with GSDMA antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Frequently Asked Questions
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