SCXA Antibody / Scleraxis

Scleraxis/SCXA is a transcription factor that is essential for the proper formation of tendons and ligaments in our bodies. It is responsible for regulating the expression of genes that are involved in tendon development, maintenance, and repair. Without Scleraxis, our tendons and ligaments would not be able to function properly, leading to a host of musculoskeletal issues. Research has shown that mutations in the SCXA gene can lead to conditions such as chronic tendon injuries, tendinopathies, and even developmental abnormalities in tendons.

Product Specifications

Specifications

Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:50-1:100

UniProt

Q7RTU7

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 172-201 from the human protein was used as the immunogen for the SCXA antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity

Format

Purified

Limitations

This SCXA antibody is available for research use only.

Storage Conditions

Aliquot the SCXA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the SCXA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Nuclear

Image Legend

IHC staining of FFPE human breast carcinoma tissue with SCXA antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.