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Phospho-LRP6 (Ser1490) Antibody / Low density lipoprotein receptor related protein 6

Product Specifications

Specifications

Western blot: 1:500-1:2000

UniProt

O75581

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Phospho-LRP6 (S1490) was used as the immunogen for the Phospho-LRP6 (Ser1490) antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG

Clone

31L42

Applications

WB

Purity

Affinity chromatography

Format

Liquid

Buffer

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/mL BSA.

Limitations

This Phospho-LRP6 (Ser1490) antibody is available for research use only.

Storage Conditions

Store the Phospho-LRP6 (Ser1490) antibody at -20°C.

Formulation

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the Phospho-LRP6 (Ser1490) antibody should be determined by the researcher.

Image Legend

Western blot analysis of Phospho-LRP6 (S1490) expression in lysate from human HeLa cells treated with Calyculin, using Phospho-LRP6 (Ser1490) antibody. A strong band is detected at ~220-230 kDa, consistent with the mature, heavily N-glycosylated and hyperphosphorylated form of LRP6, which migrates slower than the ~180 kDa unglycosylated core polypeptide.

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