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Monoglyceride lipase Antibody / MGLL

Monoglyceride lipase / MGLL is a key enzyme involved in the hydrolysis of monoacylglycerols, which are the building blocks of various lipids in the body. By breaking down these molecules, Monoglyceride lipase helps regulate lipid metabolism and plays a crucial role in energy balance and homeostasis. Studies have shown that Monoglyceride lipase deficiency can lead to disruptions in lipid metabolism, leading to conditions such as obesity, insulin resistance, and metabolic syndrome. And overexpression of Monoglyceride lipase has been linked to increased lipid breakdown and improved metabolic health. Monoglyceride lipase has also been found to regulate various signaling pathways, including those involved in inflammation, cancer, and neurodegenerative diseases.

Product Specifications

Specifications

Western blot: 0.5-2 µg/mL, Immunohistochemistry (FFPE) : 5 µg/mL, Immunofluorescence: 10 µg/mL, Flow cytometry: 1ug/million cells in 0.1ml, ELISA (peptide) LOD: 1:64000

UniProt

Q99685

Host

Goat

Reactivity

Human, Mouse

Immunogen

Amino acids QDLPHLVNADGQY were used as the immunogen for this Monoglyceride lipase antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC-P, IF, FACS, ELISA (peptide)

Purity

Antigen affinity

Format

Antigen affinity purified

Limitations

This Monoglyceride lipase antibody is available for research use only.

Storage Conditions

Aliquot and store the Monoglyceride lipase antibody at -20°C.

Formulation

0.5 mg/mL in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide

Applications Notes

Optimal dilution of the Monoglyceride lipase antibody should be determined by the researcher.

Prediction Reactivity

Rat, Dog, Pig, Cow

Image Legend

Immunofluorescent staining of fixed and permeabilized human U-2 OS cells with Monoglyceride lipase antibody (green) at 10ug/ml, Phalloidin (red) and DAPI nuclear stain (blue) .
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