SOX2 Antibody / SRY related HMG box 2

The SOX2 protein is involvement in embryonic development. It plays a significant role in maintaining the pluripotency of embryonic stem cells, ensuring that they have the potential to differentiate into any cell type within the body. Studies have shown that aberrant expression of SOX2 is associated with various types of cancer, including lung, breast, and brain tumors.

Product Specifications

Specifications

Western blot: 0.1-0.3 µg/mL, Immunohistochemistry (FFPE) : 6-8 µg/mL, Flow cytometry: 1ug/million cells in 0.1ml, ELISA (peptide) LOD: 1:32000

UniProt

P48431

Host

Goat

Reactivity

Human

Immunogen

Amino acids YNMMETELKPPGPQQ were used as the immunogen for this SOX2 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P, FACS, ELISA (peptide)

Purity

Antigen affinity

Format

Antigen affinity purified

Limitations

This SOX2 antibody is available for research use only.

Storage Conditions

Aliquot and store the SOX2 antibody at -20°C.

Formulation

0.5 mg/mL in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide

Applications Notes

Optimal dilution of the SOX2 antibody should be determined by the researcher.

Location

Cytoplasmic, nuclear

Image Legend

IHC staining of FFPE human tonsil tissue with SOX2 antibody at 8ug/ml. Required HIER: steamed antigen retrieval with pH6 citrate buffer; HRP-staining.