Plasminogen Antibody / PLG

Plasminogen (PLG) is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase (PLAU) and tissue plasminogen activator (PLAT) . The main function of plasmin is to dissolve fibrin (see, e.g., FGA) clots. Plasmin, like trypsin, belongs to the family of serine proteinases. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis.

Product Specifications

Specifications

Western blot: 0.5-1 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

P00747

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids V98-P356 from the human protein were used as the immunogen for the Plasminogen antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, Direct ELISA

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Limitations

This Plasminogen antibody is available for research use only.

Storage Conditions

Store the Plasminogen antibody at -20°C.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Plasminogen antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) rat testis, 2) rat thymus, 3) rat spleen, 4) rat lung, 5) mouse testis and 6) mouse thymus lysate with Plasminogen antibody. Predicted molecular weight ~92 kDa, may be observed at higher molecular weights due to glycosylation.