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Cd14 Antibody

This gene encodes a protein that plays an important role in the innate immune response and is expressed in monocyte/macrophage cells. This gene product acts as a co-receptor that binds several microbial and fungal molecules, including lipopolysaccharides (LPS) . This proteins LPS-binding activity is enhanced by the LPS binding protein (LBP) to allow binding to the TLR4-MD-2 co-receptor complex. The product of this gene is found in two forms, either as a soluble protein or attached to the cell surface by a glycosylphosphatidylinositol anchor.

Product Specifications

Specifications

Western blot: 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL

UniProt

P10810

Host

Rabbit

Reactivity

Mouse

Immunogen

An E.coli-derived mouse recombinant protein (amino acids D36-A260) was used as the immunogen for the Cd14 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Cd14 antibody is available for research use only.

Storage Conditions

After reconstitution, the Cd14 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Cd14 antibody should be determined by the researcher.

Image Legend

Western blot testing of mouse RAW264.7 cell lysate with Cd14 antibody. Predicted molecular weight: 40-55 kDa depending on glycosylation level.

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