Cd14 Antibody
This gene encodes a protein that plays an important role in the innate immune response and is expressed in monocyte/macrophage cells. This gene product acts as a co-receptor that binds several microbial and fungal molecules, including lipopolysaccharides (LPS) . This proteins LPS-binding activity is enhanced by the LPS binding protein (LBP) to allow binding to the TLR4-MD-2 co-receptor complex. The product of this gene is found in two forms, either as a soluble protein or attached to the cell surface by a glycosylphosphatidylinositol anchor.
Product Specifications
Specifications
Western blot: 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL
UniProt
P10810
Host
Rabbit
Reactivity
Mouse
Immunogen
An E.coli-derived mouse recombinant protein (amino acids D36-A260) was used as the immunogen for the Cd14 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This Cd14 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Cd14 antibody should be determined by the researcher.
Image Legend
Western blot testing of mouse RAW264.7 cell lysate with Cd14 antibody. Predicted molecular weight: 40-55 kDa depending on glycosylation level.
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