Phospho-MCM2 Antibody pS27
Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. [UniProt]
Product Specifications
Specifications
Western blot: 1:500-1:2000
UniProt
P49736
Host
Rabbit
Reactivity
Human
Immunogen
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
28M65
Applications
WB
Purity
Affinity chromatography
Format
Purified
Limitations
This phospho-MCM2 antibody is available for research use only.
Storage Conditions
Store the phospho-MCM2 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the phospho-MCM2 antibody should be determined by the researcher.
Image Legend
Western blot testing of lysate from 1) human HeLa cells and 2) human HeLa cells treated with alkaline phosphatase, using phospho-MCM2 antibody.
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