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Phospho-Minichromosome maintenance 2 Antibody pS108

Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. [UniProt]

Product Specifications

Specifications

Western blot: 1:500-1:2000

UniProt

P49736

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide from the sequence surrounding phosphorylated serine 108 of human MCM2 protein was used as the immunogen for the phospho-Minichromosome maintenance 2 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG

Clone

28M76

Applications

WB

Purity

Affinity chromatography

Format

Purified

Limitations

This phospho-Minichromosome maintenance 2 antibody is available for research use only.

Storage Conditions

Store the phospho-Minichromosome maintenance 2 antibody at -20°C.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the phospho-Minichromosome maintenance 2 antibody should be determined by the researcher.

Image Legend

Western blot testing of lysate from 1) human HeLa cells and 2) human HeLa cells treated with alkaline phosphatase, using phospho-MCM2 antibody.

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