Mitofilin Antibody / IMMT / MIC60
Mitochondrial inner membrane protein is a protein that in humans is encoded by the IMMT gene. IMMT (also known as mitofilin) is an inner mitochondrial membrane protein that is preferentially expressed in heart tissue and is commonly used as the marker for mitochondria. Mitofilin is known to be a critical organizer of mitochondrial cristae morphology and is indispensable for normal mitochondrial function. Three isoforms of mitofilin exist due to the alternative splicing. All three proteins of 87kD, 89kD and 80kD can be detected in immunoblot analysis with this antibody.
Product Specifications
Specifications
UniProt
Q16891
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An E.coli-derived human recombinant protein (amino acids D83-K714) was used as the immunogen for the Mitofilin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF, FACS, ELISA
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This Mitofilin antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Mitofilin antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
IHC staining of FFPE mouse heart tissue with Mitofilin antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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