CRTC2 Antibody / TORC2
CRTC2 is a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. [UniProt]
Product Specifications
Specifications
Western blot: 1:500-1:2000
UniProt
Q53ET0
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide from human CREB-regulated transcription coactivator 2 protein was used as the immunogen for the CRTC2 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
28C77
Applications
WB
Purity
Affinity chromatography
Format
Purified
Limitations
This CRTC2 antibody is available for research use only.
Storage Conditions
Store the CRTC2 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the CRTC2 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 293T cell lysate with CRTC2 antibody. Predicted molecular weight ~73 kDa.
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