MPPE1 Antibody / Metallophosphoesterase 1

MPPE1 encodes a metallophosphoesterase protein that is widely brain expressed and is a member of the calcineurin-like phosphoesterase superfamily. Phosphoesterases are involved in a variety of diverse biochemical reactions, including protein phosphorylation-dephosphorylation processes that modulate functional properties of proteins. The MPPE1 gene is located on chromosome 18p11.21 and is flanked by the G protein Golf alpha (GNAL) gene and the myo-inositol monophosphatase gene (IMPA2) . Variation in the MPPE1 gene might lead to an altered enzyme with downstream effects on protein phosphorylation involved in cellular signaling.

Product Specifications

Specifications

Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, ELISA: 0.1-0.5 µg/mL

UniProt

Q53F39

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

An E.coli-derived human recombinant protein (amino acids Y43-R329) was used as the immunogen for the MPPE1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, FACS, ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This MPPE1 antibody is available for research use only.

Storage Conditions

After reconstitution, the MPPE1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the MPPE1 antibody should be determined by the researcher.

Image Legend

Flow cytometry testing of fixed and permeabilized human RT4 cells with MPPE1 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= MPPE1 antibody.