IGSF8 Antibody / Immunoglobulin superfamily member 8 / CD316

Immunoglobulin superfamily member 8 is a protein that in humans is encoded by the IGSF8 gene. This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile) -motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.

Product Specifications

Specifications

Western blot: 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL

UniProt

Q969P0

Host

Rabbit

Reactivity

Human, Rat

Immunogen

An E.coli-derived human recombinant protein (amino acids D73-D578) was used as the immunogen for the IGSF8 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This IGSF8 antibody is available for research use only.

Storage Conditions

After reconstitution, the IGSF8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the IGSF8 antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) human K562, 2) human 293T, 3) human SH-SY5Y, 4) human HepG2 and 5) rat brain tissue lysate with IGSF8 antibody. Predicted molecular weight ~65 kDa.