COPS8 Antibody / COP9 signalosome complex subunit 8 / CSN8
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. [UniProt]
Product Specifications
Specifications
Western blot: 1:500-1:2000
UniProt
Q99627
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide from human COP9 signalosome complex subunit 8 protein was used as the immunogen for the COPS8 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
28C83
Applications
WB
Purity
Affinity chromatography
Format
Purified
Limitations
This COPS8 antibody is available for research use only.
Storage Conditions
Store the COPS8 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the COPS8 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HepG2 cell lysate with COPS8 antibody. Predicted molecular weight ~23 kDa and ~18 kDa (two isoforms) .
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