MTAP Antibody / MTA phosphorylase
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. [UniProt]
Product Specifications
Specifications
Western blot: 1:500-1:2000, Immunoprecipitation: 1:50
UniProt
Q13126
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide specific to human MTAP protein was used as the immunogen for the MTAP Antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
28M98
Applications
WB, IP
Purity
Affinity chromatography
Format
Purified
Limitations
This MTAP antibody is available for research use only.
Storage Conditions
Store the MTAP antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the MTAP antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) human 293T and 2) mouse NIH 3T3 cell lysate with MTAP antibody. Expected molecular weight: 26-38 kDa (multiple isoforms) .
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