RASGRP3 Antibody / Ras guanyl-releasing protein 3

Ras guanyl-releasing protein 3 is a protein that in humans is encoded by the RASGRP3 gene. The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 2-5 µg/mL, ELISA: 0.1-0.5 µg/mL

UniProt

Q8IV61

Host

Rabbit

Reactivity

Human

Immunogen

An E.coli-derived human recombinant protein (amino acids K8-R607) was used as the immunogen for the RASGRP3 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

IHC-P, ELISA

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This RASGRP3 antibody is available for research use only.

Storage Conditions

After reconstitution, the RASGRP3 Antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the RASGRP3 antibody should be determined by the researcher.

Location

Cytoplasmic/perinuclear

Image Legend

IHC staining of FFPE human rectum adenocarcinoma tissue with RASGRP3 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.