AKAP8 Antibody / A-kinase anchor protein 8 / AKAP 95
AKAP8 is an anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase. Acts as an anchor for a PKA-signaling complex onto mitotic chromosomes, which is required for maintenance of chromosomes in a condensed form throughout mitosis. Recruits condensin complex subunit NCAPD2 to chromosomes required for chromatin condensation; the function appears to be independent from PKA-anchoring. [UniProt]
Product Specifications
Specifications
Western blot: 1:500-1:2000
UniProt
O43823
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human A-kinase anchor protein 8 was used as the immunogen for the AKAP8 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
29A07
Applications
WB
Purity
Affinity chromatography
Format
Purified
Limitations
This AKAP8 antibody is available for research use only.
Storage Conditions
Store the AKAP8 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the AKAP8 antibody should be determined by the researcher.
Image Legend
Western blot testing of human HepG2 cell lysate with AKAP8 antibody. Predicted molecular weight ~76 kDa but routinely observed at ~95 kDa.
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