5-HT3C Antibody / 5-hydroxytryptamine receptor 3C / HTR3C
5-hydroxytryptamine receptor 3C is a protein that in humans is encoded by the HTR3C gene. The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3.
Product Specifications
Specifications
Western blot: 1-2 µg/mL, Immunofluorescence: 5 µg/mL, ELISA: 0.1-0.5 µg/mL
UniProt
Q8WXA8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An E.coli-derived human recombinant protein (amino acids D79-Q417) was used as the immunogen for the 5-HT3C antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IF, ELISA
Purity
Antigen affinity chromatography
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This 5-HT3C antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the 5-HT3C antibody should be determined by the researcher.
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