WNT5A Antibody
Protein Wnt-5a is a protein that in humans is encoded by the WNT5A gene. This gene is a member of the WNT gene family. The WNTs comprise a large class of secreted proteins that control essential developmental processes such as embryonic patterning, cell growth, migration, and differentiation. It is mapped to 3p14.3. WNT5A is highly expressed in the dermal papilla of depilated skin. This protein plays an essential role in regulating developmental pathways during embryogenesis. And this protein may also play a role in oncogenesis. WNT5A and DVL can promote axon differentiation mediated by the PAR3-PAR6-aPKC complex.
Product Specifications
Specifications
Western blot: 1-2 µg/mL, ELISA: 0.1-0.5 µg/mL
UniProt
P41221
Host
Rabbit
Reactivity
Human
Immunogen
An E.coli-derived human recombinant protein (amino acids D198-D303) was used as the immunogen for the WNT5A antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, ELISA
Purity
Antigen affinity chromatography
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This WNT5A antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the WNT5A antibody should be determined by the researcher.
Image Legend
Western blot testing of human SiHa cell lysate with WNT5A antibody. Predicted molecular weight ~41 kDa, commonly observed at 41-45 kDa.
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