HCRT Antibody / Hypocretin neuropeptide precursor
This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL
UniProt
O43612
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
A synthetic peptide specific to human HCRT protein was used as the immunogen for the HCRT antibody. The sequence is 100% homolgous in mouse and rat.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, IF
Purity
Antigen affinity chromatography
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This HCRT antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the HCRT antibody should be determined by the researcher.
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Frequently Asked Questions
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