INTS13 Antibody / Integrator complex subunit 13

Integrator Complex Subunit 13 Protein, also known as INTS13, is a subunit of the Integrator complex, which plays a critical role in the 3' end processing of small nuclear RNAs (snRNAs) . This complex is responsible for the cleavage and polyadenylation of snRNAs, which are essential for the splicing of pre-mRNA. INTS13 is specifically involved in the cleavage step of snRNA processing, highlighting its importance in gene expression regulation.

Product Specifications

Specifications

Western blot: 1-2 µg/mL, Immunofluorescence: 5 µg/mL, ELISA: 0.1-0.5 µg/mL

UniProt

Q9NVM9

Host

Rabbit

Reactivity

Human

Immunogen

An E.coli-derived human recombinant protein (amino acids M1-H254) was used as the immunogen for the INTS13 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IF, ELISA

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This INTS13 antibody is available for research use only.

Storage Conditions

After reconstitution, the INTS13 Antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the INTS13 antibody should be determined by the researcher.

Location

Nuclear, cytoplasmic

Image Legend

Immunofluorescent staining of FFPE human U-2 OS cells with INTS13 antibody (red) and Beta Tubulin mAb (green) . HIER: steam section in pH6 citrate buffer for 20 min.