Recombinant CRIPTO Antibody
GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. [UniProt]
Product Specifications
Specifications
Western blot: 1:500-1:2000
UniProt
Q9UKX7
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human Protein Cripto was used as the immunogen for the recombinant CRIPTO antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
21T86
Applications
WB
Purity
Affinity chromatography
Format
Purified
Limitations
This recombinant CRIPTO antibody is available for research use only.
Storage Conditions
Store the recombinant CRIPTO antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the recombinant CRIPTO antibody should be determined by the researcher.
Image Legend
Western blot testing of human NCCIT cell lysate with recombinant CRIPTO antibody. Predicted molecular weight ~21 kDa.
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